Small Colony Variants ofStaphylococcus aureusand Pacemaker-related Infection
نویسندگان
چکیده
منابع مشابه
Small Colony Variants of Staphylococcus aureus and Pacemaker-related Infection
I caused by Staphylococcus aureus range from mild skin infections to acute life-threatening diseases such as pneumonia, osteomyelitis, and endocarditis. However, S. aureus may also cause a chronic disease with persistent and recurrent infections. Skin and soft tissue infections, chronic osteomyelitis, and persistent infections in patients with cystic fibrosis have been associated with small col...
متن کاملBloodstream infections caused by small-colony variants of coagulase-negative staphylococci following pacemaker implantation.
Small-colony variants (SCVs) of Staphylococcus aureus cause persistent and relapsing infections. Relatively little is known regarding infections caused by SCVs of coagulase-negative staphylococci. We report two cases of pacemaker electrode infections due to SCVs of Staphylococcus epidermidis and Staphylococcus capitis. Sequence analysis of a portion of the 16S rRNA gene (16S rDNA) confirmed the...
متن کاملStaphylococcus lugdunensis Pacemaker-related Infection
We report the first known case of a device-related bloodstream infection involving Staphylococcus lugdunensis small-colony variants. Recurrent pacemaker-related bloodstream infection within a period of 10 months illustrates the poor clinical and microbiologic response even to prolonged antimicrobial drug therapy in a patient infected with this staphylococcal subpopulation.
متن کاملSmall-colony variants of Staphylococcus aureus.
Staphylococcus aureus remains a versatile and dangerous pathogen. Small-colony variants (SCVs) of S. aureus are a naturally occurring sub-population, first described nearly 100 years ago. These variants, of which there are different classes, grow slowly and have many atypical characteristics thought to be due to defective electron transport, and include minute colony forms. SCVs have been isola...
متن کاملPhenotypic and Genotypic Characteristics of Small Colony Variants and Their Role in Chronic Infection
Small colony variant (SCV) bacteria arise spontaneously within apparently homogeneous microbial populations, largely in response to environmental stresses, such as antimicrobial treatment. They display unique phenotypic characteristics conferred in part by heritable genetic changes. Characteristically slow growing, SCVs comprise a minor proportion of the population from which they arise but per...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2003
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid0910.0302000